Proteintech, 25004-1-AP, ZIC1 Polyclonal antibody

Size: 20ul / 150ul The ZIC1 (25004-1-AP) by Proteintech is a Polyclonal antibody targeting ZIC1 in WB, ELISA applications with reactivity to human, rat samples 25004-1-AP targets ZIC1 in WB, ELISA applications and shows reactivity with human, rat samples. Tested Applications Positive WB detected in: ROS1728 cells, Y79 cells, PC-12 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information ZIC1 is a member of the Zinc finger of the cerebellum (ZIC) protein family. In vertebrates, the ZIC gene family plays an important role in neural crest and subsequent cerebellar development. Mutations in ZIC family members have demonstrated that they are essential for proper development of the neural tube, left-right symmetry, and muscle and skeletal development. It has been reported that ZIC1 participates in the regulation of cell proliferation in the dorsal neural tube by inhibition of neural differentiation. Furthermore, ZIC1 is potentially involved in the oncogenesis of undifferentiated nervous system tumors. (PMID:17936758) Specification Tested Reactivity: human, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag13400 Product name: Recombinant human ZIC1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 99-447 aa of BC104848 Sequence: DFLFRNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASPNVVNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQLHGYGPMNVNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEWYV Predict reactive species Full Name: Zic family member 1 (odd-paired homolog, Drosophila) Calculated Molecular Weight: 447 aa, 48 kDa Observed Molecular Weight: ~50 kDa GenBank Accession Number: BC104848 Gene Symbol: ZIC1 Gene ID (NCBI): 7545 RRID: AB_3085766 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q15915 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.