Proteintech, 28092-1-AP, CACNA1H Polyclonal antibody

Size: 20ul / 150ul The CACNA1H (28092-1-AP) by Proteintech is a Polyclonal antibody targeting CACNA1H in WB, ELISA applications with reactivity to human samples 28092-1-AP targets CACNA1H in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Voltage-dependent T-type calcium channel subunit alpha-1H (CACNA1H) is located in the plasma membrane of various tissues, including the brain cortex, amygdala, caudate nucleus, putamen, kidney, liver, and heart. This subunit regulates muscle contraction, secretion, neurotransmission, and gene expression by forming the pore (PMID: 33985586). Predominantly, the changes observed are missense mutations associated with gain-of-function, resulting in an increased influx of calcium into adrenal cells (PMID: 33985586; 37311830). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag26094 Product name: Recombinant human CACNA1H protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1181-1280 aa of NM_001005407 Sequence: MDGRAAPGPRATPLRRAESLDPRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQ Predict reactive species Full Name: calcium channel, voltage-dependent, T type, alpha 1H subunit Calculated Molecular Weight: 259 kDa Observed Molecular Weight: 259 kDa GenBank Accession Number: NM_001005407 Gene Symbol: CACNA1H Gene ID (NCBI): 8912 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O95180 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.