Proteintech, 28903-1-AP, Phospho-MEK6 (Ser207) Polyclonal antibody

Size: 20ul / 100ul The Phospho-MEK6 (Ser207) (28903-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-MEK6 (Ser207) in WB, ELISA applications with reactivity to Human samples 28903-1-AP targets Phospho-MEK6 (Ser207) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: UV treated HEK-293 cells, HEK-293 cells, HeLa cells, Anisomycin treated HeLa cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information MAPKK6 (Dual specificity mitogen activated protein kinase kinase 6), also known as MAP2K6 / MEK6 / MKK6, is a member of MAPKK protein kinase family. MKK6 plays an important role in intracellular signaling pathways leading toward activation of the p38 MAP kinase. MEK6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. Phosphorylation of Ser207 and Thr211 by MAP3Ks is critical for MEK6 activation, and acetylation of these resides by VopA blocks MEK6 activity(PMID: 26648936). The antibody also recognizes the ser218 phosphorylation site of MEK3. Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mitogen-activated protein kinase kinase 6 Calculated Molecular Weight: 334 aa, 37 kDa Observed Molecular Weight: 35-37 kDa GenBank Accession Number: BC012009 Gene Symbol: MEK6 Gene ID (NCBI): 5608 RRID: AB_2935411 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P52564 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.