Proteintech, 29199-1-AP, Phospho-MKK7 (Ser271/Thr275) Polyclonal antibody

Size: 20ul / 100ul The Phospho-MKK7 (Ser271/Thr275) (29199-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-MKK7 (Ser271/Thr275) in WB, ELISA applications with reactivity to Human samples 29199-1-AP targets Phospho-MKK7 (Ser271/Thr275) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: Calyculin A treated HEK-293 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:16000 Background Information Dual specificity mitogen-activated protein kinase kinase 7 (MKK7), also known as MEK7 or MAP2K7, is a member of mitogen-activated kinase kinase (MAP2K) subfamily, and a key activator of c-Jun N-terminal kinase (JNK) signaling, a pathway that regulates primarily stress and inflammatory responses. MKK7 activity can be increased by either MKK7-autophosphorylation or phosphorylation of the Ser and Thr residues of the S-X-A-K-T motifs in the Kinase domain by upstream MEKK1, MEKK2, or MLK3.(PMID: 32783966, PMID: 31579105) Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mitogen-activated protein kinase kinase 7 Calculated Molecular Weight: 47 kDa Observed Molecular Weight: 47-52 kDa GenBank Accession Number: BC038295 Gene Symbol: MKK7 Gene ID (NCBI): 5609 RRID: AB_2918246 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O14733 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, and 0.05% BSA, pH 7.3. Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage.