Proteintech, 29366-1-AP, FAM83G Polyclonal antibody

Size: 20ul / 150ul The FAM83G (29366-1-AP) by Proteintech is a Polyclonal antibody targeting FAM83G in WB, ELISA applications with reactivity to human samples 29366-1-AP targets FAM83G in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: BxPC-3 cells, HCT 116 cells, HepG2 cells, U2OS cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information FAM83G is a member of the FAM83 protein family, which consists of eight members characterized by sharing a conserved N-terminal domain named DUF1669. This domain is homologous to the phospholipase D catalytic domain but lacks essential catalytic histidine residues, suggesting it is unlikely to have phospholipase activity. FAM83G, in particular, has a consensus motif for serine/threonine protein kinase D1/protein kinase C mu (PKD1/PKCμ) phosphorylation at serine residue 356 (S356), which suggests it may have a unique physiological function among the FAM83 protein family members. Furthermore, FAM83G has been identified as a novel inducer of apoptosis, with its phosphorylation at S356 modulating heat shock protein 27 (HSP27) phosphorylation and apoptosis regulation. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag28925 Product name: Recombinant human FAM83G protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 574-823 aa of NM_001039999 Sequence: NGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP Predict reactive species Full Name: family with sequence similarity 83, member G Calculated Molecular Weight: 91 kDa Observed Molecular Weight: 100 kDa GenBank Accession Number: NM_001039999 Gene Symbol: FAM83G Gene ID (NCBI): 644815 RRID: AB_3669686 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: A6ND36 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.