Proteintech, 29574-1-AP, Phospho-INPPL1 (Tyr986/987) Polyclonal antibody

Size: 20ul / 100ul The Phospho-INPPL1 (Tyr986/987) (29574-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-INPPL1 (Tyr986/987) in WB, ELISA applications with reactivity to Human, mouse samples 29574-1-AP targets Phospho-INPPL1 (Tyr986/987) in WB, ELISA applications and shows reactivity with Human, mouse samples. Tested Applications Positive WB detected in: UV treated HeLa cells, UV treated NIH/3T3 cells, HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Inositol polyphosphate phosphatase-like protein 1(INPPL1) belongs to the inositol and phosphatidylinositol 5-phosphatase family, also known as SH2 domain-containing inositol 5'-phosphatase 2(SHIP2), is ubiquitous in all organizations. SHIP2 is constitutively tyrosine-phosphorylated in chronic myeloid leukemia progenitor cells. In B cells, SHIP2 was most tyrosine phosphorylated after BCR and FC-γriib crosslinking and was associated with Shc, but not after BCR stimulation alone. It has also been shown that SHIP2 can be phosphorylated at Tyr-986 in COS-7 cells and Chinese hamster ovary cells overexpressing the insulin receptor. (PMID: 11349134) Specification Tested Reactivity: Human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: inositol polyphosphate phosphatase-like 1 Calculated Molecular Weight: 1258 aa, 139 kDa Observed Molecular Weight: 150 kDa GenBank Accession Number: BC140853 Gene Symbol: INPPL1 Gene ID (NCBI): 3636 RRID: AB_3085347 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O15357 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.