Proteintech, 30013-1-AP, CD200R1 Polyclonal antibody

Size: 20ul / 150ul The CD200R1 (30013-1-AP) by Proteintech is a Polyclonal antibody targeting CD200R1 in WB, ELISA applications with reactivity to Human samples 30013-1-AP targets CD200R1 in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: A549 cells, K-562 cells, PC-3 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Cell surface glycoprotein CD200 receptor 1 (CD200R1) is also named as CD200R, CRTR2, MOX2R and OX2R, and belongs to the CD200R family. CD200R1 is inhibitory receptor for the CD200/OX2 cell surface glycoprotein. CD200R1 is highly glycosylated, containing ten potential N-glycosylation sites (PMID: 15187158). CD200R1 limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. As an immune inhibitory molecule, CD200R1 binds to CD200, ultimately leading to inhibition of classical activation of macrophages and microglia (PMID: 24588829). Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD200 receptor 1 Observed Molecular Weight: 33-36 kDa GenBank Accession Number: BC069743 Gene Symbol: CD200R1 Gene ID (NCBI): 131450 RRID: AB_3086210 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8TD46 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.