Proteintech, 30263-1-AP, Phospho-EPHA2 (Tyr588) Polyclonal antibody

Size: 20ul / 100ul The Phospho-EPHA2 (Tyr588) (30263-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-EPHA2 (Tyr588) in WB, ELISA applications with reactivity to Human samples 30263-1-AP targets Phospho-EPHA2 (Tyr588) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: MG132 treated HepG2 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Ephrin type-A receptor 2 (EPHA2), belongs to the receptor tyrosine kinases (RTKs) family, that binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Research studies have shown that Eph receptors and ligands may be involved in many diseases including cancer (PMID: 11114742). The "reverse signaling" function, whereby the cytoplasmic domain becomes tyrosine phosphorylated, allows interactions with other proteins that may activate signaling pathways in the ligand-expressing cells. The detected molecular weight is around 110 kDa. Specification Tested Reactivity: Human Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: EPH receptor A2 Calculated Molecular Weight: 976 aa, 108 kDa Observed Molecular Weight: 110 kDa GenBank Accession Number: BC037166 Gene Symbol: EPHA2 Gene ID (NCBI): 1969 RRID: AB_2935423 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P29317 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.