Proteintech, 31138-1-AP, Phospho-TAU (Thr217) Polyclonal antibody

Size: 20ul / 100ul The Phospho-TAU (Thr217) (31138-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-TAU (Thr217) in WB, ELISA applications with reactivity to human, mouse samples 31138-1-AP targets Phospho-TAU (Thr217) in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: FAD3T mouse brain tissue, mouse brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Tau (tubulin-associated unit) is a microtubule-associated protein (also known as MAPT), expressed mainly in neurons of the central nervous system. Its primary function is to modulate microtubule dynamics for maintaining axonal cytoskeleton. Various isoforms of Tau exist due to the alternative splicing, and short isoforms around 45-69 kDa and long isoforms around 100-110 kDa have been reported in different literature (8752131,15965697). Phosphorylated tau at threonine 217 (p-tau217) is one of the emerging tau markers that has repeatedly shown more promise than other p-tau isoforms as a marker of AD pathology. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: microtubule-associated protein tau Calculated Molecular Weight: 37-46, 79-81 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC000558 Gene Symbol: TAU Gene ID (NCBI): 4137 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P10636 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.