Proteintech, 32059-1-AP, KIR2DL4/CD158d Polyclonal antibody

Size: 20ul / 150ul The KIR2DL4/CD158d (32059-1-AP) by Proteintech is a Polyclonal antibody targeting KIR2DL4/CD158d in WB, ELISA applications with reactivity to human samples 32059-1-AP targets KIR2DL4/CD158d in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HL-60 cells, NK-92 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells that regulate their responsiveness to signals received from their environment (PMID: 22934097). Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4, also known as CD158D and KIR103AS) is an unusual member of the KIRs family, which activates the cytotoxicity of NK cells. KIR2DL4 has two immunoglobulin domains and a single immunoreceptor tyrosine-based inhibition motif (ITIM) in the cytoplasmic tail with weak inhibitory potential (PMID: 12055234). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 Calculated Molecular Weight: 377 aa, 42 kDa Observed Molecular Weight: 45 kDa GenBank Accession Number: BC041611 Gene Symbol: KIR2DL4 Gene ID (NCBI): 3805 RRID: AB_3670180 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q99706 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.