Proteintech, 32308-1-AP, NRAMP1 Polyclonal antibody

Size: 20ul / 150ul The NRAMP1 (32308-1-AP) by Proteintech is a Polyclonal antibody targeting NRAMP1 in WB, ELISA applications with reactivity to human samples 32308-1-AP targets NRAMP1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HL-60 cells, Jurkat cells, THP-1 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information SLC11A1 also known as NRAMP1, belongs to the SLC11 family of solute carriers, which mediate the transport of divalent metals. NRAMP1 is a divalent metal importer specifically expressed in the membranes of late endosomes/lysosomes of professional phagocytes. It plays a crucial role in the defense against intracellular pathogens by depleting essential metal ions from endocytosed microbes, thereby preventing their proliferation(PMID: 24832660, PMID: 39824808). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 Calculated Molecular Weight: 432 aa, 48 kDa Observed Molecular Weight: 60 kDa GenBank Accession Number: BC071165 Gene Symbol: SLC11A1 Gene ID (NCBI): 6556 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: P49279 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.