Product Description
Size: 20ul / 150ul
The FAM86A (32472-1-AP) by Proteintech is a Polyclonal antibody targeting FAM86A in WB, ELISA applications with reactivity to human samples
32472-1-AP targets FAM86A in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
FAM86A is a class I lysine methyltransferase (KMT), belonging to the family of protein methyltransferases (KMTs), which produces trimethylation (K525me3) at the Lys525 site of eukaryotic translation elongation factor 2 (EEF2) and promotes the binding of eEF2 to ribosomes, thereby regulating the protein synthesis. (PMID: 38508183) FAM86A is expressed in a highly dependent manner in a variety of human cancer cell lines, suggesting that FAM86A may be a potential target for future anticancer therapy.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag38481 Product name: Recombinant human FAM86A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-330 aa of BC010084 Sequence: MAPEENAGTELLLQSFERRFLAARTLRSFPWQSLEAKLRDSSDSELLRDILHKTVKHPVCVKHPPSVKYARCFLSELIKKHEAVHTEPLDELYEALAETLMAKESTQGHRSYLLPSGGSVTLSESTAIISYGTTGLVTWDAALYLAEWAIENPAVFTNRTVLELGSGAGLTGLAICKMCRPRAYIFSDCHSRVLEQLRGNVLLNGLSLEADITAKLDSPRVTVAQLDWDVATVHQLSAFQPDVVIAADVLYCPEAIMSLVGVLRRLAACREDQRAPEVYVAFTVRNPETCQLFTTELGRAGIRWEVEPRHEQKLFPYEEHLEMAMLNLTL Predict reactive species
Full Name: family with sequence similarity 86, member A
Observed Molecular Weight: 38 kDa
GenBank Accession Number: BC010084
Gene Symbol: FAM86A
Gene ID (NCBI): 196483
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q96G04
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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