Product Description
Size: 20ul / 150ul
The ZNF589 (33033-1-AP) by Proteintech is a Polyclonal antibody targeting ZNF589 in IP, ELISA applications with reactivity to human, mouse samples
33033-1-AP targets ZNF589 in IP, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive IP detected in: mouse liver tissue
Recommended dilution
Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Background Information
ZNF589(Zinc Finger Protein 589) is a protein coding gene located at 19q13.43 in human genome, belonging to C2H2 zinc finger protein family. Most members of this family appear in the form of "KRAB-ZNF", that is, the N-terminal has a KRAB(Krüppel-associated box) transcription inhibitory domain, and the C-terminal is a DNA binding domain composed of multiple C2H2 zinc fingers connected in series. ZNF589 also follows this classic structure: KRAB-A/B box at N end, middle linker, and 11 continuous C2H2 zinc fingers at C end. Because KRAB domain can recruit KAP1/TRIM28 and other co-inhibitory complexes, ZNF589 is generally regarded as a potential transcription inhibitor. GTEx data showed that the expression of ZNF589 was low to moderate in almost all adult tissues, with the highest expression in testis, ovary, thyroid, spleen, peripheral blood leukocytes and embryonic stem cells (hESC).
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag36351 Product name: Recombinant human ZNF589 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 76-250 aa of BC166625 Sequence: ESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNPCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGGNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKSSDKRQSQVC Predict reactive species
Full Name: zinc finger protein 589
Observed Molecular Weight: 47 kDa
GenBank Accession Number: BC166625
Gene Symbol: ZNF589
Gene ID (NCBI): 51385
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q86UQ0
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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