Proteintech, 33237-1-AP, IFN-alpha 4/IFNA4 Polyclonal antibody

Size: 20ul / 150ul The IFN-alpha 4/IFNA4 (33237-1-AP) by Proteintech is a Polyclonal antibody targeting IFN-alpha 4/IFNA4 in WB, ELISA applications with reactivity to human samples 33237-1-AP targets IFN-alpha 4/IFNA4 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Recombinant protein Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information IFN-alpha 4 (IFN-α4 or IFNA4) belongs to the type I interferon family, a group of cytokines primarily produced in response to viral infections. As a key player in the innate immune response, IFN-α4 provides the body's first line of defense against pathogens by inducing an antiviral state in neighboring cells. Produced primarily by macrophages, IFN-α4 exerts its antiviral effects by binding to the interferon alpha receptor (IFNAR) on cell surfaces, thereby activating downstream immune signaling pathways . This binding triggers the expression of antiviral proteins, such as a protein kinase and an oligoadenylate synthetase, which inhibit viral RNA replication and enhance natural killer cell cytotoxicity against viruses. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Eg4962 Product name: Recombinant Human IFNA4 protein (rFc Tag)(HPLC verified) Source: mammalian cells -derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 24-189 aa of BC113642 Sequence: CDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFGFPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD Predict reactive species Full Name: interferon, alpha 4 GenBank Accession Number: BC113642 Gene Symbol: IFNA4 Gene ID (NCBI): 3441 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: P05014 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.