Proteintech, 33574-1-AP, ESS2/DGCR14 Polyclonal antibody

Size: 20ul / 150ul The ESS2/DGCR14 (33574-1-AP) by Proteintech is a Polyclonal antibody targeting ESS2/DGCR14 in WB, ELISA applications with reactivity to human samples 33574-1-AP targets ESS2/DGCR14 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: DU 145 cells, HEK-293 cells, LNCaP cells, PC-3 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:12000 Background Information ESS2 splicing factor homolog (ESS2), also named DiGeorge-syndrome critical region 14 (DGCR14), acts as a transcriptional co-activator for retinoic acid receptor-related orphan nuclear receptor gamma/gamma-t (Rorγ/γt). Ess2 is a nuclear protein with a coiled-coil domain [6] that is conserved from yeasts to humans. ESS2 is a member of the deletion gene cluster in the 22q11.2 deletion syndrome (22q11.2DS, also known as DiGeorge syndrome or CATCH 22 syndrome). The syndrome is characterized by varying defects of the heart, thymus and parathyroid glands. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag37915 Product name: Recombinant human ESS2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-250 aa of NM_022719 Sequence: METPGASASSLLLPAASRPPRKREAGEAGAATSKQRVLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLELPSAEHQAIESSQASVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQVVHKNTR Predict reactive species Full Name: DiGeorge syndrome critical region gene 14 Calculated Molecular Weight: 476aa, 53 kDa Observed Molecular Weight: 50-60 kDa GenBank Accession Number: NM_022719 Gene Symbol: DGCR14 Gene ID (NCBI): 8220 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q96DF8 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.