Proteintech, 33950-1-AP, JPH2 Polyclonal antibody

Size: 20ul / 150ul The JPH2 (33950-1-AP) by Proteintech is a Polyclonal antibody targeting JPH2 in WB, ELISA applications with reactivity to human samples 33950-1-AP targets JPH2 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Caco-2 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information The JPH2 protein (Junctophilin-2) is a key structural protein specifically expressed in cardiac and skeletal muscles. It acts as a "physical bridge" between the endoplasmic reticulum and the cell membrane (the transverse tubule system), ensuring the precise spatial positioning and stability of the calcium ion release units (calcium sparks) necessary for excitation-contraction coupling by forming connection complexes. Abnormal function of this protein is closely related to various cardiac diseases such as cardiac hypertrophy, heart failure, and arrhythmia. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Eg5481 Product name: Recombinant human JPH2 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 1-672 aa of NM_020433.4 Sequence: MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGSQRSRVSFLKSDLSSGASDAASTASLGEAAEGADEAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRRMLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARGLTKAGAKKKARKEAALAAEAEVEVEEVP Predict reactive species Full Name: junctophilin 2 Calculated Molecular Weight: 74 kDa Observed Molecular Weight: 98 kDa GenBank Accession Number: NM_020433.4 Gene Symbol: JPH2 Gene ID (NCBI): 57158 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q9BR39-1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.