Proteintech, 55228-1-AP, C4b Alpha Chain/C4b-B/C4d-B Polyclonal antibody

Size: 20ul / 150ul The C4b Alpha Chain/C4b-B/C4d-B (55228-1-AP) by Proteintech is a Polyclonal antibody targeting C4b Alpha Chain/C4b-B/C4d-B in WB, ELISA applications with reactivity to human samples 55228-1-AP targets C4b Alpha Chain/C4b-B/C4d-B in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: human blood Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular weights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody raised against 1116-1128aa of human C4b protein can recognize C4b precursor, C4b alpha chain, C4b-B, and C4d-B. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: complement component 4B (Chido blood group) Calculated Molecular Weight: 193 kDa Observed Molecular Weight: 95 kDa, 300 kDa GenBank Accession Number: NM_000592 Gene Symbol: C4B Gene ID (NCBI): 721 RRID: AB_2881291 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P0C0L5 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.