Proteintech, 55417-1-AP, CASPR Polyclonal antibody

Size: 20ul / 150ul The CASPR (55417-1-AP) by Proteintech is a Polyclonal antibody targeting CASPR in WB, IHC, IF-P, ELISA applications with reactivity to human, mouse, rat samples 55417-1-AP targets CASPR in WB, IHC, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, rat brain tissue Positive IHC detected in: mouse cerebellum tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Positive IF-P detected in: mouse cerebellum tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunohistochemistry (IHC): IHC : 1:200-1:800 Immunofluorescence (IF)-P: IF-P : 1:50-1:500 Background Information CNTNAP1, also named as CASPR, NRXN4, p190, Neurexin IV and Neurexin-4, belongs to the neurexin family. It plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. CNTNAP1 seems to demarcate the paranodal region of the axo-glial junction. In association with contactin, CNTNAP1 may have a role in the signaling between axons and myelinating glial cells. This antibody is specific to CNTNAP1. Specification Tested Reactivity: human, mouse, rat Cited Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: contactin associated protein 1 Calculated Molecular Weight: 156 kDa Observed Molecular Weight: 180-190 kDa GenBank Accession Number: NM_003632 Gene Symbol: CASPR Gene ID (NCBI): 8506 RRID: AB_11232211 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P78357 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.