Proteintech, 65059-1-Ig, Anti-Mouse CD38 (90)

Size: 100ug / 500ug The CD38 (65059-1-Ig) by Proteintech is a Monoclonal antibody targeting CD38 in FC applications with reactivity to Mouse samples 65059-1-Ig targets CD38 in FC applications and shows reactivity with Mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension Background Information CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500). Specification Tested Reactivity: Mouse Host / Isotype: Rat / IgG2a, kappa Class: Monoclonal Type: Antibody Immunogen: Mouse bone marrow pre-B cells Predict reactive species Full Name: CD38 antigen GenBank Accession Number: BC046312 Gene Symbol: Cd38 Gene ID (NCBI): 12494 RRID: AB_2918367 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: P56528 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.