Proteintech, 65103-1-Ig, Anti-Human CD40 (G28.5)

Size: 100ug / 500ug The CD40 (65103-1-Ig) by Proteintech is a Monoclonal antibody targeting CD40 in FC applications with reactivity to Human samples 65103-1-Ig targets CD40 in FC applications and shows reactivity with Human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information CD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5/CD40LG. CD40L/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497). Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG1, kappa Class: Monoclonal Type: Antibody Immunogen: N/A Predict reactive species Full Name: CD40 molecule, TNF receptor superfamily member 5 Calculated Molecular Weight: 277 aa, 31 kDa GenBank Accession Number: BC012419 Gene Symbol: CD40 Gene ID (NCBI): 958 ENSEMBL Gene ID: ENSG00000101017 RRID: AB_2881471 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: P25942 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.