Proteintech, 65253-1-Ig, Anti-Human CD64 (10.1)

Size: 100ug / 500ug The CD64 (65253-1-Ig) by Proteintech is a Monoclonal antibody targeting CD64 in FC applications with reactivity to human, monkey, non-human primates samples 65253-1-Ig targets CD64 in FC applications and shows reactivity with human, monkey, non-human primates samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses. Specification Tested Reactivity: human, monkey, non-human primates Host / Isotype: Mouse / IgG1, kappa Class: Monoclonal Type: Antibody Immunogen: Human rheumatoid synovial fluid cells and fibronectin-purified monocytes. Predict reactive species Full Name: Fc fragment of IgG, high affinity Ia, receptor (CD64) Calculated Molecular Weight: 374 aa, 43 kDa GenBank Accession Number: BC032634 Gene Symbol: FCGR1A Gene ID (NCBI): 2209 ENSEMBL Gene ID: ENSG00000150337 RRID: AB_3084911 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P12314 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.