Proteintech, 65271-1-Ig, Anti-Human CD55 (JS11)

Size: 100ug / 500ug The CD55 (65271-1-Ig) by Proteintech is a Monoclonal antibody targeting CD55 in FC applications with reactivity to human samples 65271-1-Ig targets CD55 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044). Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: N/A Predict reactive species Full Name: CD55 molecule, decay accelerating factor for complement (Cromer blood group) Calculated Molecular Weight: 41 kDa GenBank Accession Number: BC001288 Gene Symbol: CD55 Gene ID (NCBI): 1604 RRID: AB_2935140 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: P08174 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.