Proteintech, 65281-1-Ig, Anti-Human IL-7 (1C11B11)

Size: 100ug The IL-7 (65281-1-Ig) by Proteintech is a Monoclonal antibody targeting IL-7 in FC (Intra) applications with reactivity to human samples 65281-1-Ig targets IL-7 in FC (Intra) applications and shows reactivity with human samples. Tested Applications Positive FC (Intra) detected in: LPS and Brefeldin A treated human PBMCs Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.2 ug per 10^6 cells in a 100 µl suspension Background Information Interleukin-7 (IL-7) is a cytokine involved in B and T cell development. It plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes and is a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Furthermore, IL-7 can improve the antiviral function and expansion of natural killer (NK) cells and regulate the development and differentiation of dendritic cells. IL-7 has also been reported as a regulator of the development of central nervous system and myogenesis and skeletal muscle cell migration. (PMID: 29663382; 29655570; 29449560) Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Product name: HumanKine® recombinant human IL-7 protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species Full Name: interleukin 7 Calculated Molecular Weight: 20 kDa GenBank Accession Number: BC047698 Gene Symbol: IL-7 Gene ID (NCBI): 3574 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P13232 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.