Proteintech, 65560-1-MR, Anti-Human HLA-DR (L243) Mouse IgG2a Recombinant Antibody

Size: 100ug The HLA-DR (65560-1-MR) by Proteintech is a Recombinant antibody targeting HLA-DR in FC applications with reactivity to human, monkey, non-human primates samples 65560-1-MR targets HLA-DR in FC applications and shows reactivity with human, monkey, non-human primates samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information HLA-DR is a member of MHC class II molecules encoded by the human leukocyte antigen complex on the region 6p21.31 of chromosome 6. HLA-DR is composed of two non-covalently associated transmembrane glycoproteins (the α and β chains), and is primarily expressed on B lymphocytes, monocytes, dendritic cells and thymic epithelial cells (PMID: 33125816). HLA-DR participates in the antigen presentation to CD4+ or CD8+ T cells and is postulated as a general biomarker of sepsis-induced immunosuppression (PMID: 28199206, 32421903). Specification Tested Reactivity: human, monkey, non-human primates Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: Human lymphoblastoid B-cell line RPMI 8866 Predict reactive species Full Name: major histocompatibility complex, class II, DR alpha Calculated Molecular Weight: 254 aa, 29 kDa GenBank Accession Number: BC032350 Gene Symbol: HLA-DRA Gene ID (NCBI): 3122 ENSEMBL Gene ID: ENSG00000204287 RRID: AB_3670314 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P01903 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.