Proteintech, 65563-1-MR, Anti-Human CD11a (TS2/4) Mouse IgG2a Recombinant Antibody

Size: 100ug The CD11a (65563-1-MR) by Proteintech is a Recombinant antibody targeting CD11a in FC applications with reactivity to human samples 65563-1-MR targets CD11a in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human peripheral blood leukocyte Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160). Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: HLA-DR CTL line Predict reactive species Full Name: integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) Calculated Molecular Weight: 129 kDa GenBank Accession Number: BC008777 Gene Symbol: CD11a Gene ID (NCBI): 3683 ENSEMBL Gene ID: ENSG00000005844 RRID: AB_3670317 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P20701 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.