Proteintech, 65573-1-MR, Anti-Human CD226 (11A8) Mouse IgG2a Recombinant Antibody

Size: 100ug The CD226 (65573-1-MR) by Proteintech is a Recombinant antibody targeting CD226 in FC applications with reactivity to human samples 65573-1-MR targets CD226 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383). Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: Human NK Cells Predict reactive species Full Name: CD226 molecule Calculated Molecular Weight: 336 aa, 39 kDa GenBank Accession Number: BC074787 Gene Symbol: CD226 Gene ID (NCBI): 10666 ENSEMBL Gene ID: ENSG00000150637 RRID: AB_3670327 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q15762 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.