Proteintech, 65587-1-MR, Anti-Human CD62P (AK4) Mouse IgG2a Recombinant Antibody

Size: 100ug The CD62P (65587-1-MR) by Proteintech is a Recombinant antibody targeting CD62P in FC applications with reactivity to Human samples 65587-1-MR targets CD62P in FC applications and shows reactivity with Human samples. Tested Applications Positive FC detected in: Thrombin treated human peripheral blood platelets Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface. Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: Human platelets Predict reactive species Full Name: selectin P (granule membrane protein 140kDa, antigen CD62) Calculated Molecular Weight: 830 aa, 91 kDa GenBank Accession Number: BC028067 Gene Symbol: CD62P Gene ID (NCBI): 6403 RRID: AB_3670337 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P16109 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.