Proteintech, 65610-1-MR, Anti-Human CD79a (HM57) Mouse IgG2a Recombinant Antibody

Size: 100ug The CD79a (65610-1-MR) by Proteintech is a Recombinant antibody targeting CD79a in FC (Intra) applications with reactivity to human samples 65610-1-MR targets CD79a in FC (Intra) applications and shows reactivity with human samples. Tested Applications Positive FC (Intra) detected in: human PBMCs Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79a is expressed in B cell and localizes in the cell membrane. CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of human CD79a Predict reactive species Full Name: CD79a molecule, immunoglobulin-associated alpha GenBank Accession Number: BC113731 Gene Symbol: CD79A Gene ID (NCBI): 973 RRID: AB_3670357 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P11912 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.