Proteintech, 65612-1-MR, Anti-Human CD16 (3G8) Mouse IgG2a Recombinant Antibody

Size: 100ug The CD16 (65612-1-MR) by Proteintech is a Recombinant antibody targeting CD16 in FC applications with reactivity to human, monkey, non-human primates samples 65612-1-MR targets CD16 in FC applications and shows reactivity with human, monkey, non-human primates samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. Clone 3G8 recognizes both the CD16a and CD16b (PMID: 7592758). Specification Tested Reactivity: human, monkey, non-human primates Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: Fc fragment of IgG, low affinity IIIa, receptor (CD16a) Calculated Molecular Weight: 254 aa, 29 kDa GenBank Accession Number: BC017865 Gene Symbol: CD16a Gene ID (NCBI): 2214 ENSEMBL Gene ID: ENSG00000203747 RRID: AB_3670359 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P08637 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.