Proteintech, 65643-1-MR, Anti-Human CD314/NKG2D (1D11) Mouse IgG2a Recombinant Antibody

Size: 100ug The CD314/NKG2D (65643-1-MR) by Proteintech is a Recombinant antibody targeting CD314/NKG2D in FC applications with reactivity to human samples 65643-1-MR targets CD314/NKG2D in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In humans, it is expressed on NK cells, gamma delta T cells, and CD8+ alpha beta T cells (PMID: 10426993). Various families of cell surface ligands have been identified, including the MICA/MICB and ULBP proteins (PMID: 12150888). CD314 is involved in both innate and adaptive immunities, and the NKG2D/NKG2DL pathway involves multiple effector cell types for controlling tumor progression (PMID: 31720075). Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: NKL cell line Predict reactive species Full Name: killer cell lectin-like receptor subfamily K, member 1 Calculated Molecular Weight: 25 kDa GenBank Accession Number: BC039836 Gene Symbol: KLRK1 Gene ID (NCBI): 22914 RRID: AB_3670372 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P26718 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.