Proteintech, 65651-1-AR, Anti-Mouse CD3e (145-2C11) Armenian Hamster Recombinant Antibody

Size: 100ug The CD3e (65651-1-AR) by Proteintech is a Recombinant antibody targeting CD3e in FC applications with reactivity to mouse samples 65651-1-AR targets CD3e in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). Specification Tested Reactivity: mouse Host / Isotype: Armenian Hamster / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: CD3 antigen, epsilon polypeptide GenBank Accession Number: BC098236 Gene Symbol: CD3ε Gene ID (NCBI): 12501 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P22646 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.