Proteintech, 65671-1-TR, Anti-Mouse CD18 (M18/2) Rat IgG2a Recombinant Antibody

Size: 100ug The CD18 (65671-1-TR) by Proteintech is a Recombinant antibody targeting CD18 in FC applications with reactivity to mouse samples 65671-1-TR targets CD18 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse thymocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in a 100 µl suspension Background Information CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570). Specification Tested Reactivity: mouse Host / Isotype: Rat / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: integrin beta 2 GenBank Accession Number: BC145644 Gene Symbol: CD18 Gene ID (NCBI): 16414 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P11835 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.