Proteintech, 65672-1-TR, Anti-Mouse CD11b (M1/70) Rat Recombinant Antibody

Size: 100ug The CD11b (65672-1-TR) by Proteintech is a Recombinant antibody targeting CD11b in IF/ICC, FC applications with reactivity to human, mouse, rabbit, monkey, guinea pig, non-human primates samples 65672-1-TR targets CD11b in IF/ICC, FC applications and shows reactivity with human, mouse, rabbit, monkey, guinea pig, non-human primates samples. Tested Applications Positive IF/ICC detected in: RAW 264.7 cells Positive FC detected in: mouse bone marrow cells, rabbit splenocytes Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:400-1:1600 Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in a 100 µl suspension Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). Specification Tested Reactivity: human, mouse, rabbit, monkey, guinea pig, non-human primates Host / Isotype: Rat / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: integrin alpha M Calculated Molecular Weight: 127 kDa GenBank Accession Number: BC156991 Gene Symbol: CD11b Gene ID (NCBI): 16409 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: E9Q604 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.