Proteintech, 65678-1-AR, Anti-Mouse TCR beta (H57-597) Armenian Hamster IgG2a Recombinant Antibody

Size: 100ug The TCR beta (65678-1-AR) by Proteintech is a Recombinant antibody targeting TCR beta in FC applications with reactivity to mouse samples 65678-1-AR targets TCR beta in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in a 100 µl suspension Background Information T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). Specification Tested Reactivity: mouse Host / Isotype: Armenian Hamster / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: T-cell receptor beta chain Gene Symbol: TCR beta Gene ID (NCBI): 21577 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.