Proteintech, 65682-1-AR, Anti-Mouse KLRG1 (2F1) Armenian Hamster IgG2a Recombinant Antibody

Size: 100ug The KLRG1 (65682-1-AR) by Proteintech is a Recombinant antibody targeting KLRG1 in FC applications with reactivity to mouse samples 65682-1-AR targets KLRG1 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518). Specification Tested Reactivity: mouse Host / Isotype: Armenian Hamster / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: killer cell lectin-like receptor subfamily G, member 1 GenBank Accession Number: BC101953 Gene Symbol: Klrg1 Gene ID (NCBI): 50928 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O88713 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.