Proteintech, 66512-1-Ig, ING2 Monoclonal antibody

Size: 20ul / 150ul The ING2 (66512-1-Ig) by Proteintech is a Monoclonal antibody targeting ING2 in WB, ELISA applications with reactivity to Human, rat, mouse samples 66512-1-Ig targets ING2 in WB, ELISA applications and shows reactivity with Human, rat, mouse samples. Tested Applications Positive WB detected in: HSCT6 cells, T-47D cells, NIH/3T3 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program. Specification Tested Reactivity: Human, rat, mouse Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag19291 Product name: Recombinant human ING2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-280 aa of BC030128 Sequence: MLGQQQQQLYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSSQPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR Predict reactive species Full Name: inhibitor of growth family, member 2 Calculated Molecular Weight: 280 aa, 33 kDa Observed Molecular Weight: 33-35 kDa GenBank Accession Number: BC030128 Gene Symbol: ING2 Gene ID (NCBI): 3622 RRID: AB_2881875 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9H160 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.