Proteintech, 66701-1-Ig, CD21 Monoclonal antibody

Size: 20ul / 150ul The CD21 (66701-1-Ig) by Proteintech is a Monoclonal antibody targeting CD21 in WB, ELISA applications with reactivity to Human samples 66701-1-Ig targets CD21 in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: human spleen tissue Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information CD21, also known as complement receptor type 2 (CR2), complement C3d receptor, and Epstein-Barr virus receptor, is a transmembrane protein that contains a small cytoplasmic domain, a transmembrane region and an extracellular domain consisting of 15 tandem short consensus repeat sequences (PMID: 6230668; 2551147). It is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells (PMID: 26119182). CD21 binds complement fragments C3d, C3dg and iC3b and acts as a receptor for the Epstein-Barr virus (PMID: 7753047). On B cells, together with CD19 and CD81, CD21 forms a complex that functions as a co-receptor to the BCR (PMID: 7542009). It is involved in B cells activation and functions. Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag18058 Product name: Recombinant human CR2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 581-930 aa of BC136394 Sequence: QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFS Predict reactive species Full Name: complement component (3d/Epstein Barr virus) receptor 2 Calculated Molecular Weight: 1092 aa, 119 kDa Observed Molecular Weight: 150 kDa GenBank Accession Number: BC136394 Gene Symbol: CD21 Gene ID (NCBI): 1380 ENSEMBL Gene ID: ENSG00000117322 RRID: AB_2882054 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P20023 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.