Product Description
Size: 20ul / 150ul
The SERPING1/C1 Inactivator (66882-1-Ig) by Proteintech is a Monoclonal antibody targeting SERPING1/C1 Inactivator in WB, IF/ICC, ELISA applications with reactivity to Human, pig, rat samples
66882-1-Ig targets SERPING1/C1 Inactivator in WB, IF/ICC, ELISA applications and shows reactivity with Human, pig, rat samples.
Tested Applications
Positive WB detected in: human plasma tissue, human plasma, pig plasma, rat serum
Positive IF/ICC detected in: HeLa cells, HepG2 cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:8000
Immunofluorescence (IF)/ICC: IF/ICC : 1:400-1:1600
Background Information
SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein.
Specification
Tested Reactivity: Human, pig, rat
Cited Reactivity: human, rat
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag16782 Product name: Recombinant human SERPING1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 151-500 aa of BC011171 Sequence: LKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFMLWDQQHKFPVFMGRVYDPRA Predict reactive species
Full Name: serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Calculated Molecular Weight: 500 aa, 55 kDa
Observed Molecular Weight: 100 kDa
GenBank Accession Number: BC011171
Gene Symbol: SERPING1
Gene ID (NCBI): 710
RRID: AB_2882214
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P05155
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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