Product Description
Size: 20ul / 150ul
The DOCK1 (67296-1-Ig) by Proteintech is a Monoclonal antibody targeting DOCK1 in WB, ELISA applications with reactivity to human, mouse, rat samples
67296-1-Ig targets DOCK1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: HeLa cells, HEK-293 cells, HSC-T6 cells, HepG2 cells, 4T1 cells, NIH/3T3 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Background Information
DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag18069 Product name: Recombinant human DOCK1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1565-1865 aa of BC146857 Sequence: KDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQTSVDSGIVQ Predict reactive species
Full Name: dedicator of cytokinesis 1
Calculated Molecular Weight: 1865 aa, 215 kDa
Observed Molecular Weight: 215 kDa
GenBank Accession Number: BC146857
Gene Symbol: DOCK1
Gene ID (NCBI): 1793
RRID: AB_2882560
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q14185
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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