Proteintech, 68340-1-Ig, GDAP1L1 Monoclonal antibody

Size: 20ul / 150ul The GDAP1L1 (68340-1-Ig) by Proteintech is a Monoclonal antibody targeting GDAP1L1 in WB, ELISA applications with reactivity to Human, mouse, rat, pig, rabbit samples 68340-1-Ig targets GDAP1L1 in WB, ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples. Tested Applications Positive WB detected in: fetal human brain tissue, pig brain tissue, rabbit brain tissue, rat brain tissue, mouse brain tissue, pig cerebellum tissue, rabbit cerebellum tissue, rat cerebellum tissue, mouse cerebellum tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) belongs to GST superfamily. Owing to its central role in mitochondrial fission, GDAP1L1 is a homologue of GDAP1 implicated in cellular processes, such as cell death, autophagy, aging, and immune response regulation (PMID:32230997). GDAP1L1, a fission factor controlling mitochondrial fission, induces fission upon translocation from the cytosol to mitochondria in response to stress condition (PMID:34638757). Furthermore, the activity of GDAP1L1 is dependent on Drp1. GDAP1, a paralog of GDAP1L1, evokes mitochondrial fragmentation only in the presence of Drp1 in HeLa cells (PMID:19782751). Specification Tested Reactivity: Human, mouse, rat, pig, rabbit Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag27717 Product name: Recombinant human GDAP1L1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-367 aa of BC009014 Sequence: MATPNNLTPTNCSWWPISALESDAAKPAEAPDAPEAASPAHWPRESLVLYHWTQSFSSQKVRLVIAEKGLVCEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRDNIISDYDQIIDYVERTFTGEHVVALMPEVGSLQHARVLQYRELLDALPMDAYTHGCILHPELTTDSMIPKYATAEIRRHLANATTDLMKLDHEEEPQLSEPYLSKQKKLMAKILEHDDVSYLKKILGELAMVLDQIEAELEKRKLENEGQKCELWLCGCAFTLADVLLGATLHRLKFLGLSKKYWEDGSRPNLQSFFERVQRRFAFRKVLGDIHTTLLSAVIPNAFRLVKRKPPSFFGASFLMGSLGGMGYFAYWYLKKKYI Predict reactive species Full Name: ganglioside-induced differentiation-associated protein 1-like 1 Calculated Molecular Weight: 367 aa, 42 kDa Observed Molecular Weight: 38-40 kDa GenBank Accession Number: BC009014 Gene Symbol: GDAP1L1 Gene ID (NCBI): 78997 RRID: AB_3085064 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q96MZ0 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.