Proteintech, 68452-1-Ig, CAMK4 Monoclonal antibody

Size: 20ul / 150ul The CAMK4 (68452-1-Ig) by Proteintech is a Monoclonal antibody targeting CAMK4 in WB, ELISA applications with reactivity to Human, mouse, rat samples 68452-1-Ig targets CAMK4 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples. Tested Applications Positive WB detected in: rat brain tissue, mouse brain tissue, rat thymus tissue Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information CaMK4 (Calcium/calmodulin-dependent protein kinase IV) is a multifunctional serine/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225) Specification Tested Reactivity: Human, mouse, rat Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag33332 Product name: Recombinant human CAMK4 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-302 aa of BC025687 Sequence: MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTG Predict reactive species Full Name: calcium/calmodulin-dependent protein kinase IV Calculated Molecular Weight: 473 aa, 52 kDa Observed Molecular Weight: 56-65 kDa GenBank Accession Number: BC025687 Gene Symbol: CAMK4 Gene ID (NCBI): 814 RRID: AB_3085164 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q16566 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.