Proteintech, 68559-1-Ig, GBP2 Monoclonal antibody

Size: 20ul / 150ul The GBP2 (68559-1-Ig) by Proteintech is a Monoclonal antibody targeting GBP2 in WB, ELISA applications with reactivity to human samples 68559-1-Ig targets GBP2 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HT-1376 cells, Saos-2 cells, HepG2 cells, PC-3 cells, A375 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information GBP2 is a member of the GTPase family and is crucial to host immunity against pathogens. GBP2 is also used as a marker of interferon (IFN) responsiveness, because it is one of the most highly expressed genes after IFN-γ stimulation. Increased GBP2 expression is also associated with a better prognosis in breast cancer and may have a role in T-cell defense against breast cancer. Interestingly, GBP2 expression in NIH/3T3 fibroblasts inhibited Rac activation and matrix metalloproteinase-9 expression, suggesting a possible role for GBP2 in regulating cancer metastasis. The molecular weight of GBP2 is 67 kDa. (PMID: 29072687, 35383115) Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag24108 Product name: Recombinant human GBP2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 131-481 aa of BC022272 Sequence: MGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLS Predict reactive species Full Name: guanylate binding protein 2, interferon-inducible Calculated Molecular Weight: 591 aa, 67 kDa Observed Molecular Weight: 67 kDa GenBank Accession Number: BC022272 Gene Symbol: GBP2 Gene ID (NCBI): 2634 RRID: AB_3085261 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P32456 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.