Proteintech, 68652-1-Ig, COL6A2 Monoclonal antibody

Size: 20ul / 150ul The COL6A2 (68652-1-Ig) by Proteintech is a Monoclonal antibody targeting COL6A2 in WB, ELISA applications with reactivity to human samples 68652-1-Ig targets COL6A2 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: human placenta tissue, human heart tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Collagen VI, composed of three polypeptides, alpha-1(VI), alpha-2(VI), and alpha-3(VI) chains, is a beaded filament collagen found in most connective tissues. The alpha-1(VI) and alpha-2(VI) chains are 140 kDa, while the alpha-3(VI) chain is 200-300 kDa (PMID: 3792302, 3348212). COL6A2 gene encodes the alpha-2 subunit of type VI collagen. The alpha-2(VI) subunit has a calculated molecular weight of 109 kDa, and an apparent molecular weight of 140 kDa due to posttranslational modification. Mutations in COL6A2 gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag7134 Product name: Recombinant human COL6A2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 671-1019 aa of BC065509 Sequence: FEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSLAQPGFFDRFIRWIC Predict reactive species Full Name: collagen, type VI, alpha 2 Calculated Molecular Weight: 109 kDa Observed Molecular Weight: 140 kDa GenBank Accession Number: BC065509 Gene Symbol: COL6A2 Gene ID (NCBI): 1292 RRID: AB_3670394 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P12110 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.