Proteintech, 68718-1-Ig, HMMR Monoclonal antibody

Size: 20ul / 150ul The HMMR (68718-1-Ig) by Proteintech is a Monoclonal antibody targeting HMMR in WB, IF/ICC, ELISA applications with reactivity to human samples 68718-1-Ig targets HMMR in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: LNCaP cells, HEK-293 cells, HepG2 cells, Jurkat cells, K-562 cells, Ramos cells Positive IF/ICC detected in: HepG2 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunofluorescence (IF)/ICC: IF/ICC : 1:400-1:1600 Background Information Hyaluronan-mediated motility receptor (HMMR), also termed CD168, was first described by Turley in murine cells . It is reported that HMMR has an extensive coiled-coil structure (CC) that contains multiple sites for interactive partners. Initially, HMMR was considered a novel hyaluronan-mediated motility receptor and a microtubule-associated spindle assembly factor. Full-length human RHAMM is an 85  kDa coiled-coil protein that occurs both in intracellular and extracellular compartments. It has highly restricted and tightly regulated expression in most normal tissues, but is one of a number of oncogenic proteins that are exported to the cell surface in response to tissue stress by unconventional transport mechanisms. (PMID: 36750558, PMID: 30249497) Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag33723 Product name: Recombinant human HMMR protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 540-724 aa of NM_012484 Sequence: LQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPMECQESWK* Predict reactive species Full Name: hyaluronan-mediated motility receptor (RHAMM) Calculated Molecular Weight: 84 kDa Observed Molecular Weight: 84 kDa GenBank Accession Number: NM_012484 Gene Symbol: HMMR Gene ID (NCBI): 3161 RRID: AB_3670411 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: O75330 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.