Product Description
Size: 20ul / 150ul
The PRPH2 (68780-1-Ig) by Proteintech is a Monoclonal antibody targeting PRPH2 in WB, IHC, ELISA applications with reactivity to human, mouse, rat, rabbit samples
68780-1-Ig targets PRPH2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.
Tested Applications
Positive WB detected in: ARPE-19 cells, rabbit eye tissue, hTERT-RPE1 cells, rat eye tissue, mouse eye tissue, rabbit retina tissue, rat retina tissue, mouse retina tissue
Positive IHC detected in: mouse eye tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Immunohistochemistry (IHC): IHC : 1:400-1:1600
Background Information
Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).
Specification
Tested Reactivity: human, mouse, rat, rabbit
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag12555 Product name: Recombinant human PRPH2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 124-346 aa of BC074720 Sequence: GSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESEGWLLEKSVPETWKAFLESVKKLGKGNQVEAEGAGAGQAPEAG Predict reactive species
Full Name: peripherin 2 (retinal degeneration, slow)
Calculated Molecular Weight: 346 aa, 39 kDa
Observed Molecular Weight: 35-39 kDa
GenBank Accession Number: BC074720
Gene Symbol: PRPH2
Gene ID (NCBI): 5961
RRID: AB_3670425
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P23942
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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