Product Description
Size: 20ul / 150ul
The PTGDS (68783-3-Ig) by Proteintech is a Monoclonal antibody targeting PTGDS in WB, ELISA applications with reactivity to human, mouse, rat, pig, rabbit samples
68783-3-Ig targets PTGDS in WB, ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Tested Applications
Positive WB detected in: rat brain tissue, human urine sample, human plasma sample, pig brain tissue, rabbit brain tissue, mouse brain tissue
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
Glycoprotein prostaglandin D2 synthase (PTGDS), also known as L-PGDS, PGDS, and LPGDS, is a member of the lipocalin superfamily and plays dual roles in prostaglandins metabolism and lipid transport (PMID: 34743203). PTGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PTGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS is abundantly expressed in the brain and heart and has also been found in testis, prostate, kidney, spleen and leukocytes. It can be found as a collection of monomeric glycoforms with molecular weights in the 27-34 kDa range (PMID: 32430846).
Specification
Tested Reactivity: human, mouse, rat, pig, rabbit
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag34483 Product name: Recombinant human PGDS protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-190 aa of BC005939 Sequence: MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ Predict reactive species
Full Name: prostaglandin D2 synthase 21kDa (brain)
Calculated Molecular Weight: 21 kDa
Observed Molecular Weight: 28 kDa
GenBank Accession Number: BC005939
Gene Symbol: PTGDS
Gene ID (NCBI): 5730
RRID: AB_3670426
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P41222
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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