Proteintech, 68893-3-Ig, CD103 Monoclonal antibody

Size: 20ul / 150ul The CD103 (68893-3-Ig) by Proteintech is a Monoclonal antibody targeting CD103 in IF/ICC, FC, ELISA applications with reactivity to human samples 68893-3-Ig targets CD103 in IF/ICC, FC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IF/ICC detected in: 5 µg/mL PHA ( 3 days) treated human PBMCs Positive FC detected in: 5 µg/mL PHA for 3 days human PBMCs Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:500-1:2000 Flow Cytometry (FC): FC : 0.20 ug per 10^6 cells in a 100 µl suspension Background Information Integrin alpha-E (CD103) is a member of the integrin family, specifically the αEβ7 heterodimer. It plays a crucial role in the immune system, particularly in the interaction between leukocytes and epithelial cells. Integrin alpha-E (CD103) is a critical component of the immune system, particularly in the context of mucosal immunity. Its ability to bind to E-cadherin and regulate the production of IFN-I in cDCs during viral infections highlights its multifaceted role in immune regulation and disease prevention. (PMID: 33584680) Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag27410 Product name: Recombinant human Integrin alpha-E protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 147-456 aa of BC113436 Sequence: LLDPDARVDTGDCYSNKEGGGEDDVNTARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAA Predict reactive species Full Name: integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) Calculated Molecular Weight: 1179 aa, 130 kDa GenBank Accession Number: BC113436 Gene Symbol: ITGAE Gene ID (NCBI): 3682 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P38570 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.