Proteintech, 82954-2-RR, Claudin 16 Recombinant monoclonal antibody

Size: 20ul / 100ul The Claudin 16 (82954-2-RR) by Proteintech is a Recombinant antibody targeting Claudin 16 in WB, ELISA applications with reactivity to human samples 82954-2-RR targets Claudin 16 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HEK-293 cells, HepG2 cells, ACHN cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They have similar structures with four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. Claudin-16 is primarily found in the kidneys and is responsible for regulating the reabsorption of magnesium and calcium ions. Mutations in the Claudin-16 gene can lead to a rare genetic disorder called familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: claudin 16 Calculated Molecular Weight: 305 aa, 34 kDa Observed Molecular Weight: 34 kDa GenBank Accession Number: BC069682 Gene Symbol: CLDN16 Gene ID (NCBI): 10686 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9Y5I7 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.