Product Description
Size: 20ul / 100ul
The GGT1 (83304-1-RR) by Proteintech is a Recombinant antibody targeting GGT1 in WB, IHC, ELISA applications with reactivity to human samples
83304-1-RR targets GGT1 in WB, IHC, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: human kidney tissue
Positive IHC detected in: human intrahepatic cholangiocarcinoma tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Immunohistochemistry (IHC): IHC : 1:500-1:2000
Background Information
GGT1 is a transpeptidase whose activity increases the availability of amino acids, primarily cysteine, for intracellular GSH synthesis. GGT1 also plays a critical role in maintaining GSH homeostasis and defense against oxidative stress. In liver and obstructive biliary diseases, circulating GGT1 activity has widely been used for diagnosis purposes, as well as an indicator of alcohol consumption. (PMID: 31151999)
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag34209 Product name: Recombinant human GGT1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 381-470 aa of NM_013430 Sequence: TAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVG Predict reactive species
Full Name: gamma-glutamyltransferase 1
Calculated Molecular Weight: 61 kDa
Observed Molecular Weight: 24 kDa
GenBank Accession Number: NM_013430
Gene Symbol: GGT1
Gene ID (NCBI): 2678
RRID: AB_3670973
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purfication
UNIPROT ID: P19440
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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