Proteintech, 83400-5-RR, Fas/CD95 Recombinant monoclonal antibody

Size: 20ul / 100ul The Fas/CD95 (83400-5-RR) by Proteintech is a Recombinant antibody targeting Fas/CD95 in IF/ICC, ELISA applications with reactivity to human samples 83400-5-RR targets Fas/CD95 in IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IF/ICC detected in: Raji cells, Jurkat cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500 Background Information Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Fusion Protein Predict reactive species Full Name: Fas (TNF receptor superfamily, member 6) Calculated Molecular Weight: 38 kDa GenBank Accession Number: NM_000043.6 Gene Symbol: Fas/CD95 Gene ID (NCBI): 355 RRID: AB_3671051 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P25445-1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.